Pancreatitis:Advances in Pathobiology Diagnosis & Treatment > Gastroenterology

This book is the proceedings of the Falk Symposium 143 on ‘Pancreatitis: Advances in Pathobiology, Diagnosis and Treatment’, held in Freiburg, Germany, on 14--15 October 2004 (Part II of the Gastroenterology Week Freiburg): the first time in the nearly 40-year-old tradition of International Falk Symposia that pancreatitis has been the main topic of the program. The aim of this state-of-the-art postgraduate volume is two-fold. First, it is focused on the marked progress in the understanding, diagnosis and management of acute and chronic pancreatitis that has been achieved within the last two decades. Second, it emphasizes the numerous, clinically relevant problems which are still unsolved.
Progress in pancreatology is based primarily on a close cooperation between gastroenterologists, visceral surgeons, radiologists, endoscopists and basic scientists. Unfortunately, one important discipline is still largely absent ? the pathology ? because the pancreas is not accessible to routine biopsy comparable to liver biopsy. On the other hand, basic science has made major contributions recently towards an improved understanding of the pathobiology of pancreatitis.
The book provides an overview of the current knowledge of pancreatology by internationally recognized experts, who also discuss open questions and different standpoints. In pancreatology like in physics we have to recognize the idea which was expressed by the physicist and Nobel Laureate W. Pauli (1900--1958): "the question is never: will the present theory remain or not, the question is always: in what direction will it change."

Preface
ACUTE PANCREATITIS I
SECTION I: PATHOBIOLOGY OF ACUTE PANCREATITIS
Chair: C Imrie, RM Schmid
1 Where and how does acute pancreatitis begin?
ML Steer, A Sharma, X-H Tao, G Perides
2 Clinical relevance of experimental models of acute pancreatitis
J Mayerle, FU Weiss, MM Lerch
SECTION II: CLINICAL PRESENTATION, DIAGNOSIS, STAGING
Chair: CD Johnson, MV Singer
3 Acute pancreatitis: epidemiology and aetiology
PG Lankisch, P Maisonneuve, AB Lowenfels
4 Acute pancreatitis: diagnostic gold standard -- new perspectives?
L Gullo
5 Acute pancreatitis: when to perform computed tomography
PC Freeny
ACUTE PANCREATITIS II
SECTION III: CONTROVERSIAL ISSUES OF THERAPY
Chair: MW Buchler, UR Folsch
6 Controversies in the treatment of acute pancreatitis: antibiotic therapy -- when and why?
J Werner, MW Buchler
7 Acute pancreatitis: benefit of early enteral feeding?
D Bimmler
8 Sterile necrosis and/or pseudocyst -- endoscopic intervention, surgery, or wait and see?
PA Banks
9 Acute pancreatitis: evidence-based indications for surgery -- the current concept
M Schafer, S Heinrich, PA Clavien
SECTION IV: LONG-TERM COURSE AND OUTCOME
Chair: S Bank, AB Lowenfels
10 Prediction of outcome in acute pancreatitis: death and local complications
CD Johnson
11 Recovery after severe pancreatitis
V Keim
12 Recurrent acute pancreatitis
JBMJ Jansen, JPH Drenth
CHRONIC PANCREATITIS I
SECTION V: PATHOBIOLOGY OF CHRONIC PANCREATITIS
Chair: G Kloppel, D Whitcomb
13 Experimental models of pancreatic fibrogenesis
MV Apte, JS Wilson
14 Gene mutations as a cause of chronic pancreatitis
DC Whitcomb
SECTION VI: CLINICAL DIAGNOSIS AND CLASSIFICATION
Chair: P Banks, L Gullo
15 To define chronic pancreatitis
M Sarner
16 Diagnosis of early stages of chronic pancreatitis using computed tomography
PC Freeny
CHRONIC PANCREATITIS II
SECTION VII: CONTROVERSIAL ISSUES OF THERAPY
Chair: P Layer, J Mossner
17 Mechanisms of pain in chronic pancreatitis
FS Lehmann, C Beglinger
18 Chronic pancreatitis: controversies in pain therapy, medical therapeutic options
J Mossner
19 Chronic pancreatitis: endoscopic versus surgical procedures for pain relief
N Alexakis, JP Neoptolemos
SECTION VIII: TREATMENT OF COMPLICATIONS AND OUTCOME
Chair: G Adler, PG Lankisch
20 Pancreatic exocrine insufficiency: rational treatment and its pathophysiological basis
P Layer
21 Pancreatic enzyme therapy in cystic fibrosis
M Stern, A Hofmann
22 Optimal control of diabetes mellitus in pancreatitis
FJM Goke, B Goke
23 Chronic pancreatitis: precursor of carcinoma?
AB Lowenfels, P Maisonneuve
24 Mortality and survival in chronic pancreatitis: a personal and international study
S Bank, N Pooran, J Xie, R Brunner
Index

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